The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5-Methoxy-1H-indole-2-carbaldehyde(SMILESS: O=CC(N1)=CC2=C1C=CC(OC)=C2,cas:21778-81-4) is researched.Electric Literature of C10H9NO2. The article 《Organocatalytic cascade aldimine condensation/[1,6]-hydride transfer/Mannich-type cyclization: sustainable access to indole-2,3-fused diazocanes》 in relation to this compound, is published in Green Chemistry. Let’s take a look at the latest research on this compound (cas:21778-81-4).
An unprecedented organocatalytic cascade aldimine condensation/[1,6]-hydride transfer/Mannich-type cyclization of indole-2-carbaldehydes with o-aminoanilines was developed to assemble polycyclic indole-2,3-fused diazocanes in one step. This novel methodol. featured high step- and atom-economy, was redox-neutral and metal-free, and occurred at room temperature It opened a new window for the application of hydride transfer chem. in constructing medium-sized ring structures.
This literature about this compound(21778-81-4)Reference of 5-Methoxy-1H-indole-2-carbaldehydehas given us a lot of inspiration, and I hope that the research on this compound(5-Methoxy-1H-indole-2-carbaldehyde) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem