Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 885272-25-3, is researched, SMILESS is COC2=CC=C1NC(C(C1=C2)CC(=O)O)=O, Molecular C11H11NO4Journal, Natural Product Communications called Preparation of O-methyl substituted 2-oxofuro- and 2-oxopyrrolidinoindolines by reductive lactonization of oxindolylacetic acids, Author is Morales-Rios, Martha S.; Rivera-Becerril, Ernesto; Lopez-Camacho, Perla Y.; Perez-Rojas, Nadia A.; Suarez-Castillo, Oscar R., the main research direction is oxofuroindoline oxopyrrolidinoindoline preparation reductive lactonization oxindolylacetic acid.Reference of 2-(5-Methoxy-2-oxoindolin-3-yl)acetic acid.
A practical procedure for the preparation of O-methyl-substituted 3a,8-dialkyl-2-oxofuroindoline derivatives was described. A reductive lactonization of the corresponding (oxindolyl)acetic acids provides a route for the formation of this class of compounds Further transformation of 2-oxofuroindolines into 2-oxopyrrolidinoindolines and then to pyrrolidinoindolines demonstrates their versatility as key intermediates in natural products synthesis. The results of single-crystal X-ray crystallog. analyses are given for five of the studied compounds The title compounds thus formed included a 3,3a,8,8a-tetrahydro-2H-furo[2,3-b]indol-2-one (furanone) derivative (I) and (3aR,8aS)-rel-1,2,3,3a,8,8a-hexahydro-5-methoxy-1-methyl-3a,8-bis(phenylmethyl)pyrrolo[2,3-b]indole (II) and related compounds, such as 5-methoxydebromoflustramine B. The synthesis of the target compounds was achieved using 2,3-dihydro-5-methoxy-1H-indole-3-acetic acid derivatives as key intermediates.
In addition to the literature in the link below, there is a lot of literature about this compound(2-(5-Methoxy-2-oxoindolin-3-yl)acetic acid)Reference of 2-(5-Methoxy-2-oxoindolin-3-yl)acetic acid, illustrating the importance and wide applicability of this compound(885272-25-3).
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem