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Solubility values of 20 hydrazones in water, 1-octanol and hexane were determined by the isothermal saturation method. Thermophysical characteristics of fusion processes (melting points and fusion enthalpies) of the selected substances were measured by DSC method. The impact of structural modification of the molecules on solubility processes in the solvents was analyzed. Transfer processes from water to 1-octanol and from water to hexane were analyzed. Correlation equations connecting the transfer coefficients with physicochemical descriptors were obtained.
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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1856 – PubChem