September 6,2021 News New explortion of 55928-90-0

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 55928-90-0 is helpful to your research. Safety of 5-Bromopyridazin-4-amine

Safety of 5-Bromopyridazin-4-amine, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.55928-90-0, Name is 5-Bromopyridazin-4-amine, molecular formula is C4H4BrN3. In a Article,once mentioned of 55928-90-0

Synthesis and structure-activity relationship (SAR) of a series of nonsteroidal glucocorticoid receptor (GR) agonists are described. These compounds contain “diazaindole” moieties and display different transcriptional regulatory profiles in vitro and are considered “dissociated” between gene transrepression and transactivation. The lead optimization effort described in this article focused in particular on limiting the transactivation of genes which result in bone side effects and these were assessed in vitro in MG-63 osteosarcoma cells, leading to the identification of (R)-18 and (R)-21. These compounds maintained anti-inflammatory activity in vivo in collagen induced arthritis studies in mouse but had reduced effects on bone relevant parameters compared to the widely used synthetic glucocorticoid prednisolone 2 in vivo. To our knowledge, we are the first to report on selective glucocorticoid ligands with reduced bone loss in a preclinical in vivo model.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 55928-90-0 is helpful to your research. Safety of 5-Bromopyridazin-4-amine

Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2450 – PubChem