Downstream Synthetic Route Of 1178884-53-1

The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules.Read on for other articles about 1178884-53-1Safety of 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one

1178884-53-1, Name is 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one, belongs to pyridazine compound, is a common compound. Safety of 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-oneIn an article, once mentioned the new application about 1178884-53-1.

This application discloses 5-phenyl-1H-pyridin-2-one, 6-phenyl-2H-pyridazin-3-one, and 5-Phenyl-1H-pyrazin-2-one derivatives according to generic Formulae I-III: wherein, variables Q, R, X, X’, Y1, Y2, Y2′, Y3, Y4, Y5, m, and n are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of Formulae I-III and at least one carrier, diluent or excipient

The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules.Read on for other articles about 1178884-53-1Safety of 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one

Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2993 – PubChem