141-30-0, Name is 3,6-Dichloropyridazine, belongs to pyridazine compound, is a common compound. Product Details of 141-30-0In an article, once mentioned the new application about 141-30-0.
A new structural class of DGAT1 inhibitors was discovered and the structure-activity relationship was explored. The pyrrolotriazine core of the original lead molecule was changed to a pyrrolopyridazine core providing an increase in potency. Further exploration resulted in optimization of the propyl group at C7 and the discovery that the ester at C6 could be replaced by five-membered heterocyclic rings. The analogs prepared have DGAT1 IC 50 values ranging from >10 muM to 48 nM.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms.In my other articles, you can also check out more blogs about 141-30-0Product Details of 141-30-0, you can also check out more blogs aboutProduct Details of 141-30-0
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1691 – PubChem