Related Products of 492431-11-5, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 492431-11-5, 1-Boc-4-(6-Chloropyridazin-3-yl)piperazine, introducing its new discovery.
Identification and structure-guided optimization of a series of 4-(pyrazol-4-yl)-pyrimidines as selective CDK4/6 inhibitors is reported herein. Several potency and selectivity determinants were established based on the X-ray crystallographic analysis of representative compounds bound to monomeric CDK6. Significant selectivity for CDK4/6 over CDK1 and CDK2 was demonstrated with several compounds in both enzymatic and cellular assays.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 492431-11-5. In my other articles, you can also check out more blogs about 492431-11-5
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N3238 – PubChem