One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Application In Synthesis of 5-Bromopyridazin-4-amine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 55928-90-0, Name is 5-Bromopyridazin-4-amine, molecular formula is C4H4BrN3
Synthesis and structure-activity relationship (SAR) of a series of nonsteroidal glucocorticoid receptor (GR) agonists are described. These compounds contain “diazaindole” moieties and display different transcriptional regulatory profiles in vitro and are considered “dissociated” between gene transrepression and transactivation. The lead optimization effort described in this article focused in particular on limiting the transactivation of genes which result in bone side effects and these were assessed in vitro in MG-63 osteosarcoma cells, leading to the identification of (R)-18 and (R)-21. These compounds maintained anti-inflammatory activity in vivo in collagen induced arthritis studies in mouse but had reduced effects on bone relevant parameters compared to the widely used synthetic glucocorticoid prednisolone 2 in vivo. To our knowledge, we are the first to report on selective glucocorticoid ligands with reduced bone loss in a preclinical in vivo model.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Application In Synthesis of 5-Bromopyridazin-4-amine, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 55928-90-0
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2450 – PubChem