17973-86-3, 3,6-Dibromopyridazine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 3. Preparation of 3-(4-(benzyloxy)cyclohexyloxy)-6-bromopyridazine To a stirred suspension of 4-(benzyloxy)cyclohexanol (50.0 mg, 0.242 mmol) and KO’Bu (40.8 mg, 0.364 mmol) in THF (3.00 mL) was added 3,6-dibromopyridazine (115 mg, 0.485 mmol) at room temperature. The reaction mixture was stirred at 70 C. for 15 hours. The residue was diluted with EtOAc and washed with water and brine, dried over MgSO4, filtered and concentrated in vacuo. The residue was purified by column chromatography on SiO2 (Hex:EtOAc=3:1) to give the desired product as a white solid. 1H-NMR (400 MHz, CDCl3) delta 1.58 (3H, m), 1.78 (2H, m), 2.04 (2H, m), 2.23 (1H, m), 3.46, 3.57 (1H, m), 4.55 (2H, s), 5.27, 5.36 (1H, m), 6.81 (1H, m), 7.26-7.37 (5H, m), 7.45 (1H, m). LC-MS Calcd. 362.06, Found 362.80 [M+H]+., 17973-86-3
17973-86-3 3,6-Dibromopyridazine 248852, apyridazine compound, is more and more widely used in various fields.
Reference£º
Patent; CHEMIZON, A DIVISION OF OPTOMAGIC CO., LTD.; US2012/53180; (2012); A1;,
Pyridazine – Wikipedia
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