5469-70-5, Name is 3-Aminopyridazine, belongs to pyridazine compound, is a common compound. SDS of cas: 5469-70-5In an article, once mentioned the new application about 5469-70-5.
The discovery and optimization of a series of tetrahydropyridopyrimidine based extracellular signal-regulated kinase (Erks) inhibitors discovered via HTS and structure based drug design is reported. The compounds demonstrate potent and selective inhibition of Erk2 and knockdown of phospho-RSK levels in HepG2 cells and tumor xenografts.
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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N64 – PubChem