The important role of 10344-42-0

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10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, belongs to pyridazine compound, is a common compound. Product Details of 10344-42-0In an article, once mentioned the new application about 10344-42-0.

A synthetic method for the so far unknown dipyridazino[4,3-b:3′,4′- e][l,4]-diazepinone system (7a) was elaborated. Cyclisation of 6-chloro-N- (3,6-dichloropyridazin-4-yl)-3-(4-methoxybenzylamino)-N-propylpyridazine-4- carboxamide (5) under basic conditions was found to yield in addition to the expected compound (7a) an isomeric dipyridazino[3,4-b:3′,4′- e][1,4]diazepinone (7b) resulting from Smiles rearrangement. The 7a/7b ratio was found to be influenced by the nature of the base and the solvent.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3020 – PubChem