19064-67-6, 6-Chloro-3-hydroxypyridazine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Compound 2 (2.1 g, 16 mmol) was dissolved in N,N-dimethylformamide.Add cesium carbonate (10.4 g, 32 mmol),Methyl 4-bromomethylbenzoate (3.7 g, 16 mmol),Stir at room temperature and continue to stir the reaction.TLC detects the progress of the reaction,The reaction was complete after 4 hours.Add appropriate amount of ethyl acetate and dilute the extract.Washed with saturated saline,The organic phase is concentrated,Separated and purified by silica gel column chromatography (ethyl acetate / petroleum ether = 1/3).4.0 g of a white solid compound 3 was obtained in a yield of 90%.
As the paragraph descriping shows that 19064-67-6 is playing an increasingly important role.
Reference£º
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Hu Youhong; Geng Meiyu; Duan Wenwen; Ding Jian; Wan Penghui; Shen Aijun; Lu Dong; Liu Hongchun; Wei Aihuan; Zhang Minmin; Zeng Limin; Cao Jingchen; (57 pag.)CN109280032; (2019); A;,
Pyridazine – Wikipedia
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