With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.914349-19-2,4-(6-Chloropyridazin-3-yl)benzaldehyde,as a common compound, the synthetic route is as follows.
4- (6-chloropyridazin-3-yl) benzaldehyde (40 mg, 0.18 mmol)Was dissolved in methanol / dichloromethane (4: 1, 2 mL), sodium borohydride (NaBH4, 10 mg, 0.26 mmol) was gradually added at 0 C and the mixture was stirred at room temperature for 2 hours. After the reaction, ethyl acetate was added thereto, washed with brine, and the organic layer was dried over anhydrous sodium sulfate,Concentrated to give (4- (6-chloropyridazin-3-yl) phenyl) methanol(39 mg, 98%) as a yellow solid.
914349-19-2, The synthetic route of 914349-19-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Korea Research Institute of Chemical Technology; Handok Co., Ltd.; Jeong Hui-jeong; Kim Hyeong-rae; Ha Jae-du; Lee Jeong-ok; Cho Seong-yun; Choi Sang-un; Lee Jong-guk; Park Ji-hun; (45 pag.)KR101869534; (2018); B1;,
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