Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 3-Chloropyridazine. Introducing a new discovery about 1120-95-2, Name is 3-Chloropyridazine
Copper-mediated trifluoromethylation of heteroaromatic compounds by trifluoromethyl sulfonium salts
Copper is king! A convenient method for the synthesis of trifluoromethylated heteroaromatic compounds under mild conditions has been developed based on the observation that 1 can be reduced by certain metals (see scheme). Substrate 1 is assumed to be reduced by copper via a single-electron transfer mechanism, and CuCF3 is the most probable intermediate in this reaction. DMF=N,N-dimethylformamide, Tf=triflate.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 3-Chloropyridazine, you can also check out more blogs about1120-95-2
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N439 – PubChem