Synthetic Route of 53896-49-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53896-49-4, Name is Pyridazine-3-carbonitrile, molecular formula is C5H3N3. In a Article，once mentioned of 53896-49-4
Bis(allyl)-ruthenium(IV) complexes with phosphinous acid ligands as catalysts for nitrile hydration reactions
Several mononuclear ruthenium(iv) complexes with phosphinous acid ligands [RuCl2(eta3:eta3-C10H16)(PR2OH)] have been synthesized (78-86% yield) by treatment of the dimeric precursor [{RuCl(mu-Cl)(eta3:eta3-C10H16)}2] (C10H16 = 2,7-dimethylocta-2,6-diene-1,8-diyl) with 2 equivalents of different aromatic, heteroaromatic and aliphatic secondary phosphine oxides R2P(O)H. The compounds [RuCl2(eta3:eta3-C10H16)(PR2OH)] could also be prepared, in similar yields, by hydrolysis of the P-Cl bond in the corresponding chlorophosphine-Ru(iv) derivatives [RuCl2(eta3:eta3-C10H16)(PR2Cl)]. In addition to NMR and IR data, the X-ray crystal structures of representative examples are discussed. Moreover, the catalytic behaviour of complexes [RuCl2(eta3:eta3-C10H16)(PR2OH)] has been investigated for the selective hydration of organonitriles in water. The best results were achieved with the complex [RuCl2(eta3:eta3-C10H16)(PMe2OH)], which proved to be active under mild conditions (60 C), with low metal loadings (1 mol%), and showing good functional group tolerance.
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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N201 – PubChem