141-30-0, Name is 3,6-Dichloropyridazine, belongs to pyridazine compound, is a common compound. COA of Formula: C4H2Cl2N2In an article, once mentioned the new application about 141-30-0.
In the current study, some novel ethyl 6-[(substituted-phenylpiperazine]- 3(2H)-pyridazinone-2-yl propionate III and 6-[(substituted-phenylpiperazine]- 3(2H)-pyridazinone-2-yl propionohydrazide IV derivatives were synthesized as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors. The structures of these new pyridazinone derivatives were confirmed by their IR, 1H-NMR spectra and elementary analysis. 6-Substituted-3(2H)- pyridazinone-2-yl propionate IIIa-e derivatives showed significant inhibitory activity against AChE and BChE. 6-[4-(3-Trifluoromethylphenyl)-piperazine]-3(2H) -pyridazinone-2-yl propionate IIIe has been found to be the most active compound in terms of inhibition of either AChE or BChE. Compound IIIe exhibited inhibitory activity close to that of galantamine (CAS 357-70-0) and did not show any selectivity between the two enzymes. Also the antimicrobial activities of III and IV derivatives have been evaluated. All III and IV derivatives exhibited poor antibacterial activities but moderate antifungal activities. ECV ? Editio Cantor Verlag.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 141-30-0
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1838 – PubChem