With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7252-84-8,3-Amino-6-methoxypyridazine,as a common compound, the synthetic route is as follows.
7252-84-8, To a solution of 3-amino-6-methoxypyridazine (250 mg, 2.0 mmol) in acetonitrile (50 mL) was added 2-bromo-4?-nitroacetophenone (970 mg, 3.99 mmol), and then the reaction mixture was refluxed for 5.0 hours. The resulting mixture was filtered and the filter cake was dried under vacuum to give the title product (408 mg, 75.7%). The compound was characterized by the following spectroscopic data: ESI-MS (positive ion mode) m/z: 271.2 [M+1]+.
7252-84-8 3-Amino-6-methoxypyridazine 81673, apyridazine compound, is more and more widely used in various fields.
Reference£º
Patent; SUNSHINE LAKE PHARMA CO., LTD.; CHENG, Changchung; LIU, Bing; ZHANG, Yingjun; LONG, Bohua; ZHANG, Weihong; WO2015/43492; (2015); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem