Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. HPLC of Formula: C8H10Cl2N2. Introducing a new discovery about 22808-29-3, Name is 4-tert-Butyl-3,6-dichloropyridazine
Discovery of pyrrolopyridazines as novel DGAT1 inhibitors
A new structural class of DGAT1 inhibitors was discovered and the structure-activity relationship was explored. The pyrrolotriazine core of the original lead molecule was changed to a pyrrolopyridazine core providing an increase in potency. Further exploration resulted in optimization of the propyl group at C7 and the discovery that the ester at C6 could be replaced by five-membered heterocyclic rings. The analogs prepared have DGAT1 IC 50 values ranging from >10 muM to 48 nM.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.HPLC of Formula: C8H10Cl2N2, you can also check out more blogs about22808-29-3
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N2890 – PubChem