Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Sarris, Alexi J. C., once mentioned the application of 103-85-5, Name is 1-Phenylthiourea, molecular formula is C7H8N2S, molecular weight is 152.2168, MDL number is MFCD00004933, category is pyridazines. Now introduce a scientific discovery about this category, Formula: C7H8N2S.
Fast and pH-Independent Elimination of trans-Cyclooctene by Using Aminoethyl-Functionalized Tetrazines
The inverse-electron-demand Diels-Alder/pyridazine elimination tandem reaction, in which the allylic substituent on trans-cyclooctene is eliminated following reaction with tetrazines, is gaining interest as a versatile bioorthogonal process. One potential shortcoming of such currently used reactions is their propensity to proceed faster and more efficiently at lower pH, a feature caused by the nature of the tetrazines used. Here, we present aminoethyl-substituted tetrazines as the first pH-independent reagents showing invariably fast elimination kinetics at all biologically relevant pH values.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 103-85-5, Formula: C7H8N2S.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem