Brief introduction of 1120-95-2

The synthetic route of 1120-95-2 has been constantly updated, and we look forward to future research findings.

1120-95-2, 3-Chloropyridazine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a suspension of NaH (1.1 mmol) in anhydrous DMF, cooled at 0 C, a solution of the appropriate aryl chloride (1.0 mmol) and of the appropriate glycidol (1.0 mmol) in the same solvent was added dropwise. The reaction mixture was stirred at room temperature overnight, quenched with H2O and extracted with AcOEt (3 ¡Á 20 mL). The organic layers were collected, dried over Na2SO4 and concentrated under reduced pressure. The crude was purified on a silica gel column (CHCl3/AcOEt, 9:1 as eluent) to give pure compound as an oil., 1120-95-2

The synthetic route of 1120-95-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Hansen, Hanne D.; Lacivita, Enza; Di Pilato, Pantaleo; Herth, Matthias M.; Lehel, Szabolcs; Ettrup, Anders; Andersen, Valdemar L.; Dyssegaard, Agnete; De Giorgio, Paola; Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Niso, Mauro; Knudsen, Gitte M.; Leopoldo, Marcello; European Journal of Medicinal Chemistry; vol. 79; (2014); p. 152 – 163;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem