6082-66-2, 3,4,6-Trichloropyridazine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a mixture of 3,4,6-trichloropyridazine (2.0 g, 8.78 mmol) (World Patent WO2007/115947, 2007) in anhydrous dimethylformamide (15 mL) was added solid potassium carbonate (2.42 g, 17.6 mmol). The flask was cooled to 0 C. and a solution of N-Boc-piperazine (1.80 g, 9.65 mmol), in anhydrous DMF (5 mL) was added drop-wise. The mixture was allowed to warm to room temperature and stirred for a further 3 h. The reaction mixture was partitioned between ethyl acetate (50 mL) and water (50 mL). The organic layer was washed with an aqueous solution of sodium chloride (50 mL) and dried via hydrophobic frit. The resulting solution was concentrated to give a pale brown solid. The residue was purified by flash chromatography (silica gel, 20% EtOAc/isohexane) to give 3.21 g (94%) of the title compound as a pale cream solid. 1H NMR delta (ppm)(DMSO-d6): 1.40 (9 H, s), 3.27-3.34 (4 H, m), 3.50-3.62 (4H, m), 7.42 (1H, s)., 6082-66-2
As the paragraph descriping shows that 6082-66-2 is playing an increasingly important role.
Reference£º
Patent; Institute for OneWorld Health; US2010/267706; (2010); A1;,
Pyridazine – Wikipedia
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