Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Application In Synthesis of N,N’-Diphenylthiourea, 102-08-9, Name is N,N’-Diphenylthiourea, molecular formula is C13H12N2S, belongs to pyridazines compound. In a document, author is Vajekar, Shailesh N., introduce the new discover.
Choline hydroxide promoted sustainable one-pot three-component synthesis of 1H-pyrazolo[1,2-a]pyridazine-2-carbonitriles under solvent-free conditions
A sustainable one-pot three-component synthesis of novel 1H-pyrazolo[1,2-a]pyridazine-2-carbonitrile derivatives employing a highly efficient, biodegradable, and recyclable choline hydroxide catalyst under solvent-free conditions is demonstrated. The salient features of this protocol are simple workup, mild reaction conditions, short reaction time (10 min), excellent yields (up to 97%), high atom economy, column chromatography-free protocol, and eco-friendliness. Interestingly, the choline hydroxide was recycled up to five cycles without any considerable loss of efficiency. The structures of the products were deduced by their H-1 NMR, C-13 NMR, and HRLC-MS spectra.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 102-08-9. Application In Synthesis of N,N’-Diphenylthiourea.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem