The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 455-24-3, Name is 4-(Trifluoromethyl)benzoic acid, SMILES is C1=C(C=CC(=C1)C(O)=O)C(F)(F)F, in an article , author is Axundova, F. N., once mentioned of 455-24-3, Application In Synthesis of 4-(Trifluoromethyl)benzoic acid.
Synthesis of New Iminosugar Derivatives Based on (S)-(1,2,3,6-Tetrahydropyridazin-3-yl)methanol
(S)-(1,2,3,6-Tetrahydropyridazin-3-yl)methanol was synthesized in two steps by the Diels-Alder reaction of penta-2,4-dien-1-ol with diethyl azodicarboxylate in the presence of (S)-BINOL as chiral catalyst. The subsequent Boc-protection of the 2-position of the pyridazine ring, ring-closing carbonylation of the hydroxy group, and deprotection afforded a bicyclic iminosugar analog. The structure of the isolated compounds was proved by NMR, IR, and mass spectra and elemental analyses.
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Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem