Electric Literature of 39825-33-7, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 39825-33-7, Name is H-Ala-OiPr, SMILES is C[C@H](N)C(OC(C)C)=O, belongs to pyridazines compound. In a article, author is Kim, Chaewon, introduce new discover of the category.
Synthesis and Evaluation of Novel 3-Allylseleno-6-Alkylsulfonylpyridazine Derivatives with Potential Anticancer Properties
A new series of 3-allylseleno-6-alkylsulfonylpyridazines and 3-allylseleno-6-alkylsulfinylpyridazines were synthesized from 3,6-dichloropyridazine for anticancer agent development. The inhibitory effects of 3-allylseleno-6-alkylsulfonylpyridazines on human cancer cell lines were investigated. The synthesis involved thiolation, oxidation, selenylation, and Se-allylation of alkylthiols. That is, sodium methanethiolate, ethanethiol, propanethiol, butanethiol, pentanethiol, and hexanethiol were inserted into the 6-position of the pyridazine nucleus. These new synthetic compounds exhibited antiproliferative activity against human breast cancer (MCF-7), hepatocarcinoma (Hep3B), and human colon carcinoma (RKO) cells in CCK-8 assays, and are potential candidates for cancer chemotherapy.
Electric Literature of 39825-33-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 39825-33-7 is helpful to your research.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem