Electric Literature of 110-03-2, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 110-03-2, Name is 2,5-Dimethyl-2,5-hexanediol, SMILES is CC(C)(O)CCC(C)(C)O, belongs to pyridazines compound. In a article, author is de Geus, Mark A. R., introduce new discover of the category.
Fluorogenic Bifunctional trans-Cyclooctenes as Efficient Tools for Investigating Click-to-Release Kinetics
The inverse electron demand Diels-Alder pyridazine elimination reaction between tetrazines and allylic substituted trans-cyclooctenes (TCOs) is a key player in bioorthogonal bond cleavage reactions. Determining the rate of elimination of alkylamine substrates has so far proven difficult. Here, we report a fluorogenic tool consisting of a TCO-linked EDANS fluorophore and a DABCYL quencher for accurate determination of both the click and release rate constants for any tetrazine at physiologically relevant concentrations.
Electric Literature of 110-03-2, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 110-03-2 is helpful to your research.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem