Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 88-17-5, Name is 2-(Trifluoromethyl)aniline, molecular formula is C7H6F3N, belongs to pyridazines compound. In a document, author is Singh, Bholey, introduce the new discover, Quality Control of 2-(Trifluoromethyl)aniline.
Synthesis, crystal structures and biological evaluation of new pyridazine derivatives
A series of functionalized pyridazine derivatives (1-10) 4-phenyl-3,6-di(pyridine-4-yl)pyridazine (1), 3(3,6-di(pyridin-4-yl)pyridazin-4-yl)aniline (2), 4-(pyridin-3-yl)-3,6-di(pyridin-4-yl)pyridazine (3), 3,6-di(pyridin-4-yl)-4-(thiophen-2-yl)pyridazine (4), 6-methyl-1,4-di(pyridin-4-yl)-5H-pyrrolo[3,4-d]pyridazine-5,7(6H)-dione (5), 4-phenyl-3,6-di(pyridine-3-yl)pyridazine (6), 3-(3,6-di(pyridin-4-yl)pyridazin-3yl)aniline (7), 3,4,6-tri(pyridin-3-yl)pyridazine (8), 3,6-di(pyridin-3-yl)-4-(thiophen-2-yl)pyridazine (9), 6-methyl-1,4-di(pyridin-3-yl)-5H-pyrrolo[3,4-d]pyridazine-5,7(6H)-dione (10) were synthesized by one-step methodologies which also include Inverse Electron Demand Diels-Alder reaction. The compounds were isolated in high yields without any tedious purification procedures and characterized by NMR, Mass spectrometry, Elemental Analysis and X-ray diffraction techniques. The crystal structures of five compounds were studied. The pyridazines were subjected to anti-microbial evaluations where few of the compounds showed moderate to high activity against most of the bacteria and fungi presented in this study. (C) 2019 Elsevier B.V. All rights reserved.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 88-17-5. Quality Control of 2-(Trifluoromethyl)aniline.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem