Application of 35857-89-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.35857-89-7, Name is 6-Chloropyridazine-3-carbonitrile, molecular formula is C5H2ClN3. In a Article£¬once mentioned of 35857-89-7
Synthesis, anti-cancer evaluation of benzenesulfonamide derivatives as potent tubulin-targeting agents
A series of benzenesulfonamide derivatives were synthesized and evaluated for their anti-proliferative activity and interaction with tubulin. These new derivatives showed significant activities against cellular proliferative and tubulin polymerization. Compound BA-3b proved to be the most potent compound with IC50value ranging from 0.007 to 0.036 muM against seven cancer cell lines, and three drug-resistant cancer cell lines, which indicated a promising anti-cancer agent. The target tubulin was also verified by dynamic tubulin polymerization assay and tubulin intensity assay.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 35857-89-7, and how the biochemistry of the body works.Application of 35857-89-7
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N988 – PubChem