Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 932-22-9. Introducing a new discovery about 932-22-9, Name is 4,5-Dichloro-3(2H)-pyridazinone
Alkylation of 4,5-Dichloropyridazin-6-one with alpha,omega-Dibromoalkanes or 4,5-Dichloro-1-(omega-bromoalkyl)pyridazin-6-ones
Alkylations of 4,5-dichloropyridazin-6-one (1) with dibromoalkanes 2 or 3 in the presence of potassium carbonate or tetrabutylammonium bromide/potassium hydroxide were investigated under restricted condition.Reactions of 1 with 2 or 3, except for 2b and 3b, in the presence of potassium carbonate or tetrabutylammonium bromide/potassium hydroxide gave only the N-alkylation products 3 and/or 4.Alkylation of 1 with 2b or 3b in the presence of potassium carbonate yielded the N-alkylation products 3b and/or 4b and the O-alkylation product 5 as the main product, whereas treatment of 1 with 2b or 3b in the presence of tetrabutylammonium bromide/potassium hydroxide afforded selectively the N-alkylation products 3b and/or 4b.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 932-22-9, you can also check out more blogs about932-22-9
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N2333 – PubChem