Application of 41933-33-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.41933-33-9, Name is 2-Benzyl-4,5-dichloropyridazin-3(2H)-one, molecular formula is C11H8Cl2N2O. In a Article£¬once mentioned of 41933-33-9
Synthesis of Pyrazolo<3,4-d>pyridazines from 5-(1-Methylhydrazino)-pyridazines by Means of the Vilsmeier-Haack Reaction
Reaction of 2-substituted 5-(1-methylhydrazino)-3(2H)-pyridazinones (2a-d) with dimethylformamide-phosphorus oxychloride afforded 5-substituted 1,5-dihydro-1-methyl-4H-pyrazolo<3,4-d>pyridazin-4-ones (3a-d) in good yields.However, concurrent formation of 5-substituted 2,5-dihydro-2-(2-substituted 1-chlorovinyl)-4H-pyrazolo<3,4-d>pyridazin-4-ones (6a-c, 12, 13) (minor products) and the 1-methyl-4H-derivatives (3a-c) (major ones) was observed, when starting with the corresponding 2-substituted 5-(2-acetyl-1-methylhydrazino)-3(2H)-pyridazinones (5a-c, 9, 10) under similar conditions.A plausible mechanism for the reaction is proposed.Keywords – pyridazine; pyrazolo<3,4-d>pyridazine; Vilsmeier reagent; tri-n-butyltin chloride; sodium borohydride; stereoisomer; photoisomerization; vinyl radical
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 41933-33-9
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3208 – PubChem