In heterogeneous catalysis, the catalyst is in a different phase from the reactants. COA of Formula: C10H6Cl2N2O, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 1698-53-9, name is 4,5-Dichloro-2-phenylpyridazin-3(2H)-one. In an article£¬Which mentioned a new discovery about 1698-53-9
Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors
Methicillin resistant Staphylococcus aureus (MRSA) is a major health problem that has created a pressing need for new antibiotics. Compounds that inhibit the S. aureus SrtA sortase may function as potent anti-infective agents as this enzyme attaches virulence factors to the cell wall. Using high-throughput screening, we have identified several compounds that inhibit the enzymatic activity of the SrtA. A structure-activity relationship (SAR) analysis led to the identification of several pyridazinone and pyrazolethione analogs that inhibit SrtA with IC50 values in the sub-micromolar range. Many of these molecules also inhibit the sortase enzyme from Bacillus anthracis suggesting that they may be generalized sortase inhibitors.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 1698-53-9, help many people in the next few years.COA of Formula: C10H6Cl2N2O
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Pyridazine – Wikipedia,
Pyridazine | C4H4N3112 – PubChem