Reference of 932-22-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 932-22-9, 4,5-Dichloro-3(2H)-pyridazinone, introducing its new discovery.
Antimicrobial and antioxidant evaluation of some novel synthesized pyridazinone derivatives
This study presents the synthesis and spectral analysis of novel pyridazinone derivatives. Cyclization reaction of mucochloric acid and semicarbazide hydrochloride in the presence of aqueous ethanol afforded 4,5-dichloro-2Hpyridazin- 3-one (1). Novel compounds were synthesized by treating the 4,5-dichloro-2H-pyridazin-3-one (1) with substituted aldehyde and amine derivatives. All synthesized compounds were screened for their in vitro antibacterial, antifungal activities by using the agar cup plate method. The newly synthesized compounds showed antimicrobial activity against all the strains. Compounds 3b and 3c showed very good antifungal activity against candida albicans and Aspergillus niger (minimal inhibitory concentration [MIC] = 12.5 mug/mL). Some compounds showed good activity against Gram (+ve) bacteria and Gram (-ve) bacteria. Antioxidant study was done by using DPPH fee radical scavenging activity. Antioxidant activity assay showed that compound 3b had highest scavenger activity.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 932-22-9. In my other articles, you can also check out more blogs about 932-22-9
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N2357 – PubChem