141-30-0, Name is 3,6-Dichloropyridazine, belongs to pyridazine compound, is a common compound. category: pyridazineIn an article, once mentioned the new application about 141-30-0.
Cp*IrIII-Catalyzed [3+2] Annulations of N-Aryl-2-aminopyrimidines with Sulfoxonium Ylides to Access 2-Alkyl Indoles Through C?H Bond Activation
The iridium-catalyzed aromatic C?H alkylation followed by intramolecular annulation reactions between N-aryl-2-aminopyridines and sulfoxonium ylides for the synthesis of 2-alkyl indoles is described. This highly efficient and step-economical cyclization reaction displays excellent functional group compatibility and regioselectivity. Afterwards, the directing group in C?H alkylation can be readily removed to obtain the free N?H indoles. Thus, the sulfoxonium ylide, a carbene precursor, is proved as a useful surrogate of diazo compounds in C?H activation chemistry.
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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1805 – PubChem