Reference of 65202-50-8, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 65202-50-8, Name is Methyl 6-chloropyridazine-3-carboxylate, molecular formula is C6H5ClN2O2. In a Article£¬once mentioned of 65202-50-8
SYNTHESIS OF 6-ALKYLAMINO-3-PYRIDAZINECARBOXYLIC ACID DERIVATIVES FROM METHYL 6-CHLORO-3-PYRIDAZINECARBOXYLATE
The synthesis of methyl 6-alkylamino-3-pyridazinecarboxylates (4a-c) was accomplished by the following reaction sequence.On treatment of methyl 6-chloro-3-pyridazinecarboxylate (1) with methanolic ammonia, 6-chloro-3-pyridazinecarboxamide (5) was precipitated almost quantitatively, which reacted with primary alkylamines to give the corresponding 6-alkylamino-3-pyridazinecarboxamide (6a-c).These products were smoothly converted into the methyl esters (4a-c) by treatment with methanol in the presence of boron trifluoride etherate.The reaction of 1 with butylamine in THF ga ve a complicated mixture in which N-butyl-6-chloro-3-pyridazinecarboxamide (2), N-butyl-6-butylamino-3-pyridazinecarboxamide (3), 4b, and 1 were involved.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 65202-50-8. In my other articles, you can also check out more blogs about 65202-50-8
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N2434 – PubChem