Application of 17285-36-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.17285-36-8, Name is 5,6-Dichloropyridazin-3(2H)-one, molecular formula is C4H2Cl2N2O. In a Article£¬once mentioned of 17285-36-8
Synthesis and Chemistry of Some Pyridazine Nucleosides Related to Certain 5-Substituted Pyrimidine Nucleosides
Condensation of 3,4-dichloro-6-<(trimethylsilyl)oxy>pyridazine (3) with 1-O-acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose (4), by the stannic chloride catalyzed procedure, has furnished 3,4-dichloro-1-(2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)pyridazin-6-one (5).Nucleophilic displacement of the chloro groups and removal of the benzoyl blocking groups from 5 has furnished 3-chloro-4-methoxy-, 3,4-dimethoxy-, 4-amino-3-chloro-, 3-chloro-4-methylamino-, 3-chloro-4-hydroxy-, and 4-hydroxy-3-methoxy-1-beta-D-ribofuranosylpyridazin-6-one.An unusual reaction of 5 with dimethylamine is reported.Condensation of 4,5-dichloro-3-nitro-6-<(trimethylsilyl)oxy>pyridazine with 4 yielded 4,5-dichloro-3-nitro-1-(2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)pyridazin-6-one (24).Nucleophilic displacement of the aromatic nitro group from 24 is discussed.Condensation of 3 with 3,5-di-O-p-toluoyl 2-deoxy-D-erythro-pentofuranosyl chloride (28) afforded an alpha,beta mixture of 2-deoxy nucleosides.The syntheses of certain 3-substituted pyridazine 2′-deoxy nucleosides are reported.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 17285-36-8
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N2386 – PubChem