Photoredox-catalysed chlorination of quinoxalin-2(1H)-ones enabled by using CHCl3 as a chlorine source was written by Wu, Mei-Chun;Li, Ming-Zhi;Chen, Jia-Yi;Xiao, Jun-An;Xiang, Hao-Yue;Chen, Kai;Yang, Hua. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2022.Synthetic Route of C6H4ClN3 This article mentions the following:
A photoredox-catalyzed chlorination of quinoxalin-2(1H)-ones was developed by using CHCl3 as a chlorine source, thus affording various 3-chloroquinoxalin-2(1H)-ones in moderate to high yields. This protocol is characterized by mild reaction conditions, excellent regioselectivity, and readily available chlorination agent. Considering the operational simplicity and low cost of this chlorination approach, this developed method offers an innovative pathway for rapid incorporation of chlorine functionality into heteroarenes, and will inspire broader exploitation of new chlorination strategies. In the experiment, the researchers used many compounds, for example, 3-Chloroimidazo[1,2-b]pyridazine (cas: 60903-17-5Synthetic Route of C6H4ClN3).
3-Chloroimidazo[1,2-b]pyridazine (cas: 60903-17-5) belongs to pyridazine derivatives. The pyridazine derivatives are mostly present in biologically active compounds and are also present with different pharmacophores. In the past decade, X-ray data were reported with regard to the characterization and structural elucidation of a number of pyridazine-metal complexes, including pyridazine ligands with zinc, nickel, copper, cadmium and ruthenium.Synthetic Route of C6H4ClN3
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem