Reactions of N-heteroarylformamide oximes and N-heteroarylacetamide oximes with N,N-dimethylformamide dimethyl acetal. Synthesis of 2-methyl-s-triazolo[1,5-x]azines and N-methylcyanoaminoazines was written by Stanovnik, Branko;Stimac, Anton;Tisler, Miha;Vercek, Bojan. And the article was included in Journal of Heterocyclic Chemistry in 1982.Category: pyridazine This article mentions the following:
N-Heteroarylformamide oximes RNHCH:NOH (R = diazinyl, triazinyl) were converted with Me2NCH(OMe)2 into MeNRCN, as the main products. In some instances, RNHCN and some other products were also formed. On the other hand, RNMeCH:NOH were cyclized under the same reaction conditions into 2-methyl-s-triazolo[1,5-x]azines. RNHCMe:NOMe and RNMeCMe:NOMe were prepared from RN:CHNMe2 or RN:CMeNMe2 and MeONH2. In the experiment, the researchers used many compounds, for example, 3-Aminopyridazine (cas: 5469-70-5Category: pyridazine).
3-Aminopyridazine (cas: 5469-70-5) belongs to pyridazine derivatives. The pyridazine structure is also found within the structure of several drugs such as cefozopran, cadralazine, minaprine, pipofezine, and hydralazine. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.Category: pyridazine
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem