Relations between structure and activity of maleic hydrazide analogs and related compounds was written by Parups, E.;Hoffman, I.;Morley, H. V.. And the article was included in Canadian Journal of Biochemistry and Physiology in 1962.Formula: C5H6N2O2 This article mentions the following:
The growth- inhibiting activities of a number of compounds structurally related to maleic hydrazide (I) were examined by the technique of bud-growth inhibition. The degree of inhibitory activity of I derivatives depended on tile ease with which the plant can split off substituents. Straight-chain compounds which partially resemble I were not as active as the parent compound, and ring closure was necessary for full activity. Residue data for some of the tested compounds showed that activity failure was not due to lack of uptake and translocation. The anal. procedure for I is shown to be valid for the quant. determination of hydroxymethyl-I and N-benzoyl-I. In the experiment, the researchers used many compounds, for example, 1,2-Dihydro-4-methyl-3,6-pyridazinedione (cas: 5754-18-7Formula: C5H6N2O2).
1,2-Dihydro-4-methyl-3,6-pyridazinedione (cas: 5754-18-7) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. In the past decade, X-ray data were reported with regard to the characterization and structural elucidation of a number of pyridazine-metal complexes, including pyridazine ligands with zinc, nickel, copper, cadmium and ruthenium.Formula: C5H6N2O2
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem