Ag-catalyzed decarboxylative acylation of pyridazines using α-keto acids in aqueous media was written by Wang, Shengqiang;Xu, Xiaobo;Zou, Dapeng;Xu, Qijie. And the article was included in Tetrahedron Letters in 2021.Safety of 3-Methoxypyridazine This article mentions the following:
An efficient and general protocol for Ag-Catalyzed decarboxylative acylation of pyridazines using α-keto acids as acylation reagent in aqueous media has been described. This method provides a new avenue for the synthesis of diverse array of acylated pyridazines with different substitution patterns. The reaction proceeds smoothly in water under mild conditions and exhibits a good functional group tolerance. In the experiment, the researchers used many compounds, for example, 3-Methoxypyridazine (cas: 19064-65-4Safety of 3-Methoxypyridazine).
3-Methoxypyridazine (cas: 19064-65-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine and derivatives coordinate readily with transition metals to form complexes and catalysts with synthetic utility.Safety of 3-Methoxypyridazine
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem