Photochemistry. VI. Photo-induced methylation of pyridazines was written by Tsuchiya, Takashi;Arai, Heihachiro;Igeta, Hiroshi. And the article was included in Chemical & Pharmaceutical Bulletin in 1972.Recommanded Product: 19064-65-4 This article mentions the following:
Irradiation of pyridazine (I, R = R1 = H) (MeOH containing 5% HCl) gave II (R = R1 = H) and III (R = R1 = H). I (R = H, R1 = Me) gave II (R = H, R1 = Me; R = Me, R1 = H) and III (R = H, R1 = Me). I (R = MeO, R1 = H) gave II (R = H, R1 = MeO; R = Me, R1 = MeO). I (R = R1 = Me) gave II (R = R1 = Me) and III (R = R1 = Me). I (R = Me, R1 = MeO) gave only II (R = Me, R1 = MeO). I (R = Me, R1 = Cl; R = R1 = Cl; R = Cl, R1 = Ph, gave the 5-methylated and 4,5-dimethylated compounds resp. I (R = Cl, R1 = H) (IV) did not give monomethylation, but gave III (R = Cl, R1 = H) (1-2%), due to decomposition of IV. In the experiment, the researchers used many compounds, for example, 3-Methoxypyridazine (cas: 19064-65-4Recommanded Product: 19064-65-4).
3-Methoxypyridazine (cas: 19064-65-4) belongs to pyridazine derivatives. Pyridazine and phthalazine have quite different spectroscopic properties compared with their isomers, pyrazine and quinoxaline. In the past decade, X-ray data were reported with regard to the characterization and structural elucidation of a number of pyridazine-metal complexes, including pyridazine ligands with zinc, nickel, copper, cadmium and ruthenium.Recommanded Product: 19064-65-4
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem