Pyridazines. XXIII. Synthesis of N-substituted 1,4-dihydropyridazines was written by Kaneko, Chisato;Tsuchiya, Takashi;Igeta, Hiroshi. And the article was included in Chemical & Pharmaceutical Bulletin in 1974.Recommanded Product: 3-Methoxypyridazine This article mentions the following:
1-Methylpyridazinium salts, derived from pyridazines I to VI, were reduced with NaBH4 to give the corresponding 1-methyl-1,6-dihydropyridazines VII in 40-60% yields. Pyridazines I to VI were reduced with NaBH4 in the presence of MeO2CCl to afford 1-methoxycarbonyl-1,6-dihydropyridazines VIII and their 1,4-isomers IX, in total 35-65% yields, ratio of which depended on the kinds of the substituents. Thus, I gave little of the corresponding IX, while V gave little VIII. In the experiment, the researchers used many compounds, for example, 3-Methoxypyridazine (cas: 19064-65-4Recommanded Product: 3-Methoxypyridazine).
3-Methoxypyridazine (cas: 19064-65-4) belongs to pyridazine derivatives. Pyridazine-based compounds continued to be a great source of biologically active compounds as evidenced by the number of publications which emerged in 2021. The activity depends upon the changes of substituted groups in the pyridazine ring system resulting in different biological activities. In addition, the natural pyrimidine bases uracil, thymine, and cytosine, which are constituents of the nucleic acids, are found to be the most important naturally occurring diazines.Recommanded Product: 3-Methoxypyridazine
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem