Piras, Sandra published the artcileSynthesis and evaluation of gastroprotective activity of omeprazole-related benzimidazole, imidazo[4,5-b]pyridine and quinoxaline 2-substituted derivatives, Safety of (6-Methoxypyridazin-3-yl)methanol, the publication is Farmaco (1993), 48(9), 1249-59, database is CAplus and MEDLINE.
Twenty title compounds, bearing either a substituted arylmethylmercapto group or an arylmethylsulfinyl group in position 2, were prepared (general methods given) in order to evaluate their antiulcer and gastroprotective activity in rats with a ligated pylorus, in comparison with omeprazole (50 mg/kg, i.m.). Approx. one-third of these compounds had a moderate activity, being about half as potent as omeprazole. Some structure-activity parameters are briefly discussed.
Farmaco published new progress about 89532-79-6. 89532-79-6 belongs to pyridazine, auxiliary class Pyridazine,Alcohol,Ether, name is (6-Methoxypyridazin-3-yl)methanol, and the molecular formula is C6H8N2O2, Safety of (6-Methoxypyridazin-3-yl)methanol.
Referemce:
https://en.wikipedia.org/wiki/Pyridazine,
Pyridazine | C4H4N2 – PubChem