Landquist, Justus K.’s team published research in Journal of the Chemical Society [Section] C: Organic in 1971 | CAS: 7145-60-0

Journal of the Chemical Society [Section] C: Organic published new progress about Demethylation. 7145-60-0 belongs to class pyridazine, name is 6-Chloro-N,N-dimethylpyridazin-3-amine, and the molecular formula is C6H8ClN3, Category: pyridazine.

Landquist, Justus K. published the artcilePyridazines. II. Reaction of polychloropyridazines with trimethylamine, Category: pyridazine, the main research area is chloropyridazine amination; pyridazines chloro amination; triazine chloro amination; pyrimidines chloro amination; cyanuric chloride amination; trimethylamine amination pyridazines; ammoniums pyridazines.

3,6-Dichloro-, 3,4,6-trichloro-, 3,4,5-trichloro-, and 3,4,5,6-tetrachloropyridazine reacted with Me3N to give trimethylpyridazinylammonium chlorides, which, with the exception of (5,6-dichloro-3-pyridazinyl)ammonium chloride, underwent demethylation in the reaction mixture at room temperature to give (dimethylamino)pyridazines. The position of substitution was governed by steric requirements. 4,6-Dichloropyrimidine, 4,5,6-trichloropyrimidine, cyanuric chloride, and 4-butoxy-3,6-dichloropyridazine were also dimethylaminated by Me3N.

Journal of the Chemical Society [Section] C: Organic published new progress about Demethylation. 7145-60-0 belongs to class pyridazine, name is 6-Chloro-N,N-dimethylpyridazin-3-amine, and the molecular formula is C6H8ClN3, Category: pyridazine.

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem