Cookson, R. F.’s team published research in Journal of the Chemical Society, Perkin Transactions 9: Physical Organic Chemistry in 1972 | CAS: 7145-60-0

Journal of the Chemical Society, Perkin Transactions 9: Physical Organic Chemistry published new progress about Hammett basicity pyridazine; pyridazone oxygen protonation Hammett; protonation pyridazine mechanism. 7145-60-0 belongs to class pyridazine, name is 6-Chloro-N,N-dimethylpyridazin-3-amine, and the molecular formula is C6H8ClN3, Application of 6-Chloro-N,N-dimethylpyridazin-3-amine.

Cookson, R. F. published the artcileBasicities of pyridazine derivatives, Application of 6-Chloro-N,N-dimethylpyridazin-3-amine, the main research area is Hammett basicity pyridazine; pyridazone oxygen protonation Hammett; protonation pyridazine mechanism.

The Hammett free-energy relation was used to correlate the differences in basicity of six 3-(dimethylamino)pyridazines, five 3-chloropyridazines, and seven 3-pyridazones with substituent constants; protonation occurred ortho to the Me2N group of the (dimethylamino)pyridazines, meta to the Cl of the chloropyridazines, and on the exocyclic O of the pyridazones.

Journal of the Chemical Society, Perkin Transactions 9: Physical Organic Chemistry published new progress about Hammett basicity pyridazine; pyridazone oxygen protonation Hammett; protonation pyridazine mechanism. 7145-60-0 belongs to class pyridazine, name is 6-Chloro-N,N-dimethylpyridazin-3-amine, and the molecular formula is C6H8ClN3, Application of 6-Chloro-N,N-dimethylpyridazin-3-amine.

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem