《Formation of a 3-phenyl-4-hydroxy-6-chloropyridazine derivative for GC with ECD and MS detection and its application to trace analysis》 was published in Mikrochimica Acta in 1982. These research results belong to Landvoigt, Werner; Malissa, Hans Jr.; Winsauer, Karl. Recommanded Product: 4,6-Dichloro-3-phenylpyridazine The article mentions the following:
The determination of Pyridate (I) [55512-33-9] and the metabolite CL 9673 (II, 6-chloro-4-hydroxy-3-phenylpyridazine) [40020-01-7] is described. The method permits the determination of both compounds sep. and is applicable to corn and rape crops. The reaction of pentafluorobenzoyl chloride [2251-50-5] with II, important in the assay, is described. The product 6-chloro-4-pentafluorobenzoyl-3-phenylpyridazine [83607-25-4] is unstable; when the reaction is run in dioxan or THF solvent, 4,6-dichloro-3-phenylpyridazine [40020-05-1], a stable compound, is formed. This chloro derivative is easily determined by TLC, with detection limits of ∼1 μg/mL. Trace amounts are determined by an alternate method wherein, following separation of I and II by chromatog., II is brominated with POBr3, and determined by capillary gas chromatog. coupled with mass spectrometry. I is determined by saponification to II, and then determined as the brominated derivative as described. Detection limits are 10 ng/g.4,6-Dichloro-3-phenylpyridazine(cas: 40020-05-1Recommanded Product: 4,6-Dichloro-3-phenylpyridazine) was used in this study.
4,6-Dichloro-3-phenylpyridazine(cas: 40020-05-1) belongs to pyridazine. The pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, cardiotonic, vasodilator, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, neuroleptic, sedative-hypnotic, anticonvulsant, immunosuppressant, antiarrhythmic, and hypocholesterolaemic. Recommanded Product: 4,6-Dichloro-3-phenylpyridazine
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem