Nakagome, Takenari published the artcile< Syntheses of pyridazine derivatives. IV. Synthesis of 4-aminopyridazines.>, Reference of 20744-39-2, the main research area is AMINES/chemistry; HEXAMETHONIUM COMPOUNDS/chemistry.
Pyridazine 1-oxide (5.1 g.) in 10 ml. concentrated H2SO4, 12 ml. 12% fuming H2SO4, and 7.5 ml. fuming HNO3 heated 5 hrs. at 105-10°, the product poured into ice-H2O, taken up in CHCl3 and washed with NaHCO3 and concentrated gave 8% 4-nitropyridazine I-oxide; picrate m. 81-2°. Similarly were prepared the following nitro compounds (compound, % yield and m.p. given): 4-nitro-6-methylpyridazine 1-oxide, 56, 120-1°; 3,6-dimethyl-4-nitropyridazine 1-oxide, 83, 117-18°; 3-methoxy-4-nitro-6-methylpyridazine 1-oxide, 81, 114-15°; 3-chloro-4-nitro-6-methylpyridazine 1-oxide (I), 46, 103°. The above 4-NO2 compounds (0.04) mole in 30 ml. MeOH and 1 ml. 4N NaOMe refluxed 1 hr., the MeOH removed, the residue extracted with CHCl3 and chromatographed on Al2O3 gave the following 4-MeO compounds (product, % yield and m.p. given): 4-methoxypyridazine 1-oxide, 30, 123-4°; 4-methoxy-3-methylpyridazine 1-oxide, 0.4, 105-6°; 3-methyl-4,6-dimethoxypyridazine 1 oxide, 40, 148-9°. Catalytic reduction of 4-nitro compds, in MeOH with Raney Ni gave the following amino compounds (product, % yield and m.p. given): 4-aminopyridazine, 75, 131-2°; 3-methyl-4-aminopyridazine, 70, 162-3°; 3,6-dimethyl-4-aminopyridazine, 91, 162-3°; 3-methyl-4-amino-6-chloropyridazine, 70, 158-9°.
Yakugaku Zasshi published new progress about 20744-39-2. 20744-39-2 belongs to class pyridazine, and the molecular formula is C4H5N3, Reference of 20744-39-2.
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem