Katritzky, A. R.; Pojarlieff, I. published the artcile< The kinetics and mechanism of electrophilic substitution of heteroaromatic compounds. XVI. Acid-catalyzed hydrogen exchange of some pyridazine derivatives>, Reference of 20744-39-2, the main research area is kinetics substitution heteroaromatics; substitution heteroaromatics kinetics; heteroaromatics kinetics substitution; mechanism substitution heteroaromatics; pyridazine substitution; hydrogen exchange pyridazines.
4-Aminopyridazine exchanges in acid solution as the conjugate acid at the 5-position. In the low acidity region, the conjugate acid exchanges by the ylide mechanism at the 3- and 6-positions. Pyridazin-4-one exchanges by the acid-catalyzed mechanism as the neutral species at the 5-position; ylide-mechanism exchange on the conjugate acid occurs at the 3- and 6-positions. Pyridazin-3-one exchanges in acid solution at the 5-position; the mechanism probably involves a hydrated species. Rate constants are measured and discussed. 19 references.
Journal of the Chemical Society [Section] B: Physical Organic published new progress about Entropy. 20744-39-2 belongs to class pyridazine, and the molecular formula is C4H5N3, Reference of 20744-39-2.
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem