Barlin, Gordon B.;Yap, C. Yoot published 《Some 3-halopyridazines》. The research results were published in《Australian Journal of Chemistry》 in 1977.Application In Synthesis of Methyl 6-bromopyridazine-3-carboxylate The article conveys some information:
3-Halogenopyridazines including 3-fluoro-6-methyl- and 3-iodo-pyridazines; Me 3-fluoro-, 3-bromo- and 3-iodopyridazine-6-carboxylates and some intermediates were prepared Thus, Me 3-hydroxypyridazine-6-carboxylate was treated with POCl3 to give Me 3-chloropyridazine-6-carboxylate. To complete the study, the researchers used Methyl 6-bromopyridazine-3-carboxylate (cas: 65202-52-0) .
The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate.Application In Synthesis of Methyl 6-bromopyridazine-3-carboxylate It is also found within the structure of several drugs such as cefozopran, cadralazine, minaprine, pipofezine, and hydralazine.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem