The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-Methoxy-1H-indole-2-carbaldehyde, is researched, Molecular C10H9NO2, CAS is 21778-81-4, about Selective Synthesis of 5,6-Dihydroindolo-[1,2-a]quinoxalines and 6,7-Dihydroindolo-[2,3-c]quinolines by Orthogonal Copper and Palladium Catalysis, the main research direction is dihydroindoloquinoxaline dihydroindoloquinoline preparation copper palladium catalyst; Ugi four component reaction.Safety of 5-Methoxy-1H-indole-2-carbaldehyde.
In combination with the Ugi four-component reaction, two important indole-fused heterocycles were prepared in two steps from readily accessible starting materials. From the same set of Ugi adducts 5, 5,6-dihydroindolo[1,2-a]quinoxalines were rapidly generated in excellent yields by a copper-catalyzed N-H arylation pathway, whereas 6,7-dihydroindolo[2,3-c]quinolones were obtained by palladium-catalyzed C-H arylations in good yields without the protection of the indole N1 moiety. Microwave heating was used to accelerate these intramol. C-N and C-C bond-forming reactions performed under controlled reaction conditions.
After consulting a lot of data, we found that this compound(21778-81-4)Safety of 5-Methoxy-1H-indole-2-carbaldehyde can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem