Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 21778-81-4, is researched, SMILESS is O=CC(N1)=CC2=C1C=CC(OC)=C2, Molecular C10H9NO2Journal, Article, Organic Letters called Asymmetric Sequential Corey-Chaykovsky Cyclopropanation/Cloke-Wilson Rearrangement for the Synthesis of 2,3-Dihydrofurans, Author is Zhou, Yiming; Li, Ning; Cai, Wei; Huang, You, the main research direction is alkynyl isothiocineole indolyl acrylonitrile diastereoselective enantioselective Cloke Wilson rearrangement; progaryl sulfonium salt indolyl acrylonitrile diastereoselective Cloke Wilson rearrangement; indolyl furan preparation Corey Chaykovsky cyclopropanation.COA of Formula: C10H9NO2.
The first sequential Corey-Chaykovsky cyclopropanation/Cloke-Wilson rearrangement between propargyl sulfonium salts and acrylonitrile derivatives was developed, affording the tetra-substituted 2,3-dihydrofurans in generally excellent yields (57-98%) with good diastereoselectivities (7:1-18:1). In addition, chiral propargyl sulfonium salt is also suitable for this strategy, giving the optically active 2,3-dihydrofurans with good enantioselectivities. This reaction sequence was designed upon in situ generated 10π-conjugated structures from the dearomatization of indole fragments and subsequent intramol. 1,6-addition
Compounds in my other articles are similar to this one(5-Methoxy-1H-indole-2-carbaldehyde)COA of Formula: C10H9NO2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem