Extracurricular laboratory: Synthetic route of 21778-81-4

Compounds in my other articles are similar to this one(5-Methoxy-1H-indole-2-carbaldehyde)Synthetic Route of C10H9NO2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Synthetic Route of C10H9NO2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 5-Methoxy-1H-indole-2-carbaldehyde, is researched, Molecular C10H9NO2, CAS is 21778-81-4, about Catalytic Asymmetric [3 + 2] Annulation via Indolyl Copper-Allenylidene Intermediates: Diastereo- and Enantioselective Assembly of Pyrrolo[1,2-a]indoles. Author is Zhang, Jian; Ni, Tao; Yang, Wu-Lin; Deng, Wei-Ping.

A catalytic asym. decarboxylative [3 + 2] annulation via indolyl copper-allenylidene amphiphilic intermediates has been developed. This protocol offers a straightforward method for the synthesis of biol. important pyrrolo[1,2-a]indoles bearing contiguous quaternary and tertiary stereogenic centers with excellent diastereo- and enantioselectivities (up to >20:1 dr and >99% ee). In addition, the diversity-oriented synthesis of pyrrolo[1,2-a]indoles was achieved via versatile transformations of the alkyne-containing cycloadducts.

Compounds in my other articles are similar to this one(5-Methoxy-1H-indole-2-carbaldehyde)Synthetic Route of C10H9NO2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem